Infection means — Dr. Nishtha Tripathi Patel is an ESGO-certified gynaecological oncosurgeon offering specialist consultations and surgical care at Sterling Hospitals, KD Hospital and Welcare Speciality Hospital in Ahmedabad. This page covers infection means for patients, families and referring doctors looking for evidence-based, India-context information.
On this page
- HPV: What Every Woman Needs to Know
- High-Risk vs Low-Risk HPV
- What a Positive HPV Test Means
- Prevention: Vaccination and Screening
Infection means — HPV: What Every Woman Needs to Know
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. It is so prevalent that most sexually active adults will be exposed to HPV at some point in their lives — estimates suggest 80% lifetime exposure. In the vast majority of cases, the immune system clears the infection within two years without any symptoms, treatment, or lasting consequence.
But in a minority of women, certain high-risk HPV strains — particularly HPV 16 and HPV 18 — establish persistent infection in the cervical cells. This persistent infection drives the cellular changes that can, over many years, progress to cervical cancer. HPV is responsible for essentially 100% of cervical cancers and a significant proportion of vaginal, vulvar, anal, oropharyngeal, and penile cancers.
High-Risk vs Low-Risk HPV
- Low-risk types (HPV 6, 11) — cause genital warts (condylomata acuminata); rarely lead to cancer
- High-risk types (HPV 16, 18, 31, 33, 45, and others) — cause the cellular changes (CIN, VAIN, VIN) that precede cervical, vaginal, and vulvar cancer; no visible symptoms in most women
What a Positive HPV Test Means
A positive HPV test on a cervical smear or co-test is not a cancer diagnosis and should not cause panic. It means a high-risk HPV strain has been detected in cervical cells. The next step depends on whether cellular abnormalities (dyskaryosis) are also present. If the smear is normal but HPV-positive, a repeat test in 12 months is usually recommended. If abnormal cells are found alongside HPV, a colposcopy (examination of the cervix under magnification) is arranged.
Prevention: Vaccination and Screening
HPV vaccination (Gardasil-9 protects against 9 strains including HPV 16 and 18) is most effective when given before sexual activity begins — ideally at 9–14 years — but has proven benefit up to age 45 in clinical trials. Vaccination does not replace cervical screening; vaccinated women still require regular smear tests.
Cervical screening (Pap smear or HPV co-test) every 3–5 years from age 21–25 is the cornerstone of cervical cancer prevention. In India, uptake of cervical screening remains low — many cases of cervical cancer that I see at advanced stages could have been detected as CIN on a smear years earlier.
For HPV testing, cervical smear, or colposcopy in Ahmedabad, contact Dr. Nishtha Tripathi Patel at +91 76988 00333.